Lapin A A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1976;76(7):1084-9.
The author studied the action of a Soviet preparation Metindion in 22 patients with serial epileptic seizures and in 16 patients with an epileptic status. The studies demonstrated a high anticonvulsive activity in serial fits. In epileptical states the action of metindion was less expressed. Its combination with diazepam preparations and barbiturates appeared to have a more expressed and prolonged anticonvulsive action. Metindion is most effective when used at initial stages of a convulsive condition.
作者对苏联制剂美替啶在22例连续性癫痫发作患者和16例癫痫持续状态患者中的作用进行了研究。研究表明,美替啶在连续性发作中具有很高的抗惊厥活性。在癫痫状态下,美替啶的作用表现较弱。它与地西泮制剂和巴比妥类药物联合使用时,似乎具有更明显和持久的抗惊厥作用。美替啶在惊厥状态的初始阶段使用时最为有效。