Klinger W
Neurologische Abteilung, Poliklinik Maxim Zetkin Karl-Marx-Stadt.
Psychiatr Neurol Med Psychol (Leipz). 1989 Jul;41(7):400-5.
During observation of 92 pregnancies, epileptic seizures, pregnancy complications and complications regarding the newborns were noticed with 67 women having epilepsy and correlated by means of following therapeutic aspects: without anticonvulsive therapy, monotherapy, combined therapy. Most of the attacks suffered women that were treated by combined therapy. Pregnancy and birth complications appeared nearly to the same extent more with patients under mono- and combined therapy than with patients without therapeutic treatment. Most frequently we saw complications and malformations with regard to the children in that group of mothers that had been treated by an anticonvulsive combined therapy.
在对92例妊娠进行观察期间，67例患有癫痫的女性出现了癫痫发作、妊娠并发症及新生儿并发症，并根据以下治疗方面进行了关联分析：未进行抗惊厥治疗、单一疗法、联合疗法。接受联合疗法治疗的女性发作次数最多。单一疗法和联合疗法治疗的患者出现妊娠和分娩并发症的几率几乎相同，且高于未接受治疗的患者。在接受抗惊厥联合疗法治疗的母亲群体中，其子女出现并发症和畸形的情况最为常见。
