Gershteĭn L M, Pigareva Z D
Zh Nevropatol Psikhiatr Im S S Korsakova. 1976;76(7):997-1002.
The authors used the interferometrical method to determine the content and concentration of the proteins in the neuron cytoplasma of the III and V layer in the motor and visual areas of the brain cortex in rabbits in normal conditions and prolonged light deprivation (from the moment of birth up to 2 1/2 months). These data were accompanied by measurements of the neuron area. It was demonstrated that the absence of visual impulses leads to a morphochemical underdevelopment of the neurons in the visual cortex layers. Such underdevelopment was expressed in a decrease in the size of the neurons and protein content in the cytoplasma compared to the control group. In the neurons of the III and V layer of the motor cortex of the same animals there were changes of a compensatory character (an increase in the size of the neurons, content and concentration of proteins in the cytoplasma). In this respect the authors discuss the question of the influence of specific visual and other forms of impulsation on the morphochemical differentiation of neurons in the studied brain cortex.
作者采用干涉测量法,测定正常条件下及长期光照剥夺(从出生至2个半月)的家兔大脑皮层运动区和视觉区III层和V层神经元胞质中蛋白质的含量和浓度。这些数据还伴有对神经元面积的测量。结果表明,视觉冲动的缺失会导致视觉皮层各层神经元的形态化学发育不全。与对照组相比,这种发育不全表现为神经元大小减小以及胞质中蛋白质含量降低。在同一动物运动皮层的III层和V层神经元中出现了代偿性变化(神经元大小增加,胞质中蛋白质的含量和浓度增加)。在这方面,作者讨论了特定视觉及其他形式的冲动对所研究大脑皮层神经元形态化学分化的影响问题。