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[毒性甲状腺肿合并糖尿病患者内分泌性眼病的治疗特点]

[Peculiarities of treating endocrine ophthalmopathy in patients with toxic goiter combined with diabetes mellitus].

作者信息

Zefirova G S, Nefedova T S

出版信息

Klin Med (Mosk). 1998;76(4):32-4.

PMID:9613079
Abstract

Thyroid pathology is among autoimmune diseases the incidence of which is now on the increase. Endocrine ophthalmology (EO) often accompanying thyroid disorders may cause deterioration or loss of vision. EO can be corrected by several methods. The most pronounced effect is achieved by x-ray therapy on the orbit and intermittent glucocorticosteroid (GCS) large-dose therapy. GCS, however, affect carbohydrate metabolism. In physiological levels, GCS effects on regulation of carbohydrate metabolism are not significant, but high GCS concentrations may provoke hyperglycemia and even steroid diabetes.

摘要

甲状腺疾病属于自身免疫性疾病,目前其发病率正在上升。常伴随甲状腺疾病的内分泌性眼病(EO)可能会导致视力下降或丧失。EO可以通过多种方法进行矫正。对眼眶进行X射线治疗和间歇性大剂量糖皮质激素(GCS)治疗可取得最显著的效果。然而,GCS会影响碳水化合物代谢。在生理水平上,GCS对碳水化合物代谢调节的影响并不显著,但高浓度的GCS可能会引发高血糖甚至类固醇糖尿病。

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