Sternlo J E, Sandin R H
Department of Anaesthesia, Kalmar County Hospital, Sweden.
Anaesthesia. 1998 Apr;53(4):378-81. doi: 10.1046/j.1365-2044.1998.00312.x.
Since first commented upon by Lamarche in 1984, several cases of recurrent respiratory arrest after alfentanil infusions have been reported. In all these cases the alfentanil infusions have been used to supplement conventional anaesthetic techniques with nitrous oxide and/or inhalational agents and in most cases rather high total alfentanil doses have been administered. We have seen two cases of severe recurrent respiratory depression in healthy patients after relatively minor procedures performed under total intravenous anaesthesia with propofol-alfentanil infusions, air-oxygen ventilation and muscle relaxation, where the alfentanil doses administered were quite small. These cases are presented in detail and compared within a tabulated presentation with the earlier published cases of alfentanil-related recurrent respiratory depression.
自1984年拉马尔什首次对此进行评论以来，已有多例阿芬太尼输注后反复出现呼吸骤停的病例报告。在所有这些病例中，阿芬太尼输注均用于补充氧化亚氮和/或吸入性麻醉剂的传统麻醉技术，且在大多数情况下，阿芬太尼的总剂量相当高。我们在健康患者中观察到两例严重的反复呼吸抑制，这些患者在丙泊酚-阿芬太尼输注、空气-氧气通气和肌肉松弛的全静脉麻醉下接受了相对较小的手术，所给予的阿芬太尼剂量相当小。本文详细介绍了这些病例，并以表格形式与早期发表的与阿芬太尼相关的反复呼吸抑制病例进行了比较。
