色素性青光眼综合征中的钕钇铝石榴石激光虹膜切开术：一项超声生物显微镜研究

Nd:YAG laser iridotomy in pigment dispersion syndrome: an ultrasound biomicroscopic study.

作者信息

Carassa R G, Bettin P, Fiori M, Brancato R

机构信息

Department of Ophthalmology and Visual Sciences, University of Milano, H San Raffaele, Italy.

出版信息

Br J Ophthalmol. 1998 Feb;82(2):150-3. doi: 10.1136/bjo.82.2.150.

DOI:10.1136/bjo.82.2.150

PMID:9613380

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1722484/

Abstract

AIMS

Ultrasound biomicroscopy was used to study the shape of the iris and the iridolenticular contact in pigment dispersion syndrome (PDS) eyes, to compare them with matched normal eyes, and to assess the morphological effects of laser iridotomy in PDS eyes.

METHODS

50 eyes of 50 patients suffering from PDS (group 1), and 15 normal eyes of 15 subjects matched for age and refraction (group 2), were studied by ultrasound biomicroscopy (UBM, Humphrey-Zeiss). Nd:YAG laser iridotomy was proposed to the 30 PDS patients with concave iris and 18 underwent the treatment.

RESULTS

The iris was concave in 27 eyes in group 1, and three more eyes showed a concave iris during accommodation. Among normals, iris concavity was present in two eyes. The height of the iris convexity was -0.15 (0.24) mm (range -0.65 to +0.21), in the eyes of group 1, whereas it was +0.07 (0.10) mm (range -0.21 to +0.16) in group 2 (p < 0.0012). Group 1 had greater iridolenticular contact than group 2: 1.55 (0.78) mm (range 0.30-2.88) and 1.07 (0.61) (range 0.30-2.50; p = 0.0304). After laser iridotomy, only one eye still had a concave iris. Pre- and post-treatment deflections were -0.35 (0.18) mm (range -0.61 to -0.05) and +0.01 (0.06) mm (range -0.12 to +0.17), respectively (p < 0.0001). Pre- and post-treatment iridolenticular contact was 2.10 (0.65) mm (range 0.70-2.88) and 0.93 (0.38) mm (range 0.4-1.75), respectively (p < 0.0001). After laser iridotomy, the treated irises were flatter than normal (p = 0.0207), whereas the iridolenticular contact was not significantly different.

CONCLUSIONS

Laser iridotomy can restore a normal iris shape and iridolenticular contact in eyes suffering from PDS.

摘要

目的

采用超声生物显微镜研究色素播散综合征（PDS）患眼的虹膜形态及虹膜晶状体接触情况，与配对的正常眼进行比较，并评估激光虹膜切开术对PDS患眼的形态学影响。

方法

对50例PDS患者的50只患眼（第1组）以及15例年龄和屈光度匹配的受试者的15只正常眼（第2组）进行超声生物显微镜（UBM，Humphrey-Zeiss）检查。向30例虹膜凹陷的PDS患者建议行Nd:YAG激光虹膜切开术，其中18例接受了该治疗。

结果

第1组中27只眼的虹膜呈凹陷状，另有3只眼在调节时呈现凹陷虹膜。正常眼中，有2只眼存在虹膜凹陷。第1组患眼的虹膜凸度高度为-0.15（0.24）mm（范围-0.65至+0.21），而第2组为+0.07（0.10）mm（范围-0.21至+0.16）（p<0.0012）。第1组的虹膜晶状体接触比第2组更明显：分别为1.55（0.78）mm（范围0.30 - 2.88）和1.07（0.61）（范围0.30 - 2.50；p = 0.0304）。激光虹膜切开术后，只有1只眼仍有凹陷虹膜。治疗前和治疗后的偏移分别为-0.35（0.18）mm（范围-0.61至-0.05）和+0.01（0.06）mm（范围-0.12至+0.17）（p<0.0001）。治疗前和治疗后的虹膜晶状体接触分别为2.10（0.65）mm（范围0.70 - 2.88）和0.93（0.38）mm（范围0.4 - 1.75）（p<0.0001）。激光虹膜切开术后，治疗后的虹膜比正常虹膜更平坦（p = 0.0207），而虹膜晶状体接触无显著差异。