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Programmed cell death and Parkinson's disease.

作者信息

Burke R E

机构信息

Department of Neurology, Columbia University, New York, NY, USA.

出版信息

Mov Disord. 1998;13 Suppl 1:17-23.

PMID:9613714
Abstract
摘要

相似文献

1
Programmed cell death and Parkinson's disease.程序性细胞死亡与帕金森病
Mov Disord. 1998;13 Suppl 1:17-23.
2
Early signs of neuronal apoptosis in the substantia nigra pars compacta of the progressive neurodegenerative mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid model of Parkinson's disease.帕金森病1-甲基-4-苯基-1,2,3,6-四氢吡啶/丙磺舒渐进性神经退行性小鼠模型黑质致密部神经元凋亡的早期迹象。
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3
The molecular mechanisms of dopamine toxicity.多巴胺毒性的分子机制。
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Overexpression of alpha-synuclein in rat substantia nigra results in loss of dopaminergic neurons, phosphorylation of alpha-synuclein and activation of caspase-9: resemblance to pathogenetic changes in Parkinson's disease.大鼠黑质中α-突触核蛋白的过表达导致多巴胺能神经元丧失、α-突触核蛋白磷酸化及半胱天冬酶-9激活：类似于帕金森病的致病变化。
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5
Down-regulation of alpha-synuclein expression can rescue dopaminergic cells from cell death in the substantia nigra of Parkinson's disease rat model.α-突触核蛋白表达的下调可挽救帕金森病大鼠模型黑质中的多巴胺能细胞免于细胞死亡。
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6
Dopamine-induced, genotoxic activation of programmed cell death. A role in nigrostriatal neuronal degeneration in Parkinson's disease?多巴胺诱导的程序性细胞死亡的基因毒性激活。在帕金森病黑质纹状体神经元变性中起作用？
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7
Oxidative mechanisms in nigral cell death in Parkinson's disease.帕金森病中黑质细胞死亡的氧化机制
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8
Role of apoptosis in the pathogenesis of Parkinson's disease: A novel therapeutic opportunity?细胞凋亡在帕金森病发病机制中的作用：一种新的治疗契机？
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Distinct nuclear and cytoplasmic localization of caspase cleavage products in two models of induced apoptotic death in dopamine neurons of the substantia nigra.
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Functional neuroanatomy of the basal ganglia in Parkinson's disease.帕金森病中基底神经节的功能神经解剖学
Adv Neurol. 2003;91:9-18.

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