Agostino R, Berardelli A, Currà A, Accornero N, Manfredi M
Dipartimento Scienze Neurologiche, Università di Roma La Sapienza, Rome, Italy.
Mov Disord. 1998 May;13(3):418-21. doi: 10.1002/mds.870130308.
A retrospective analysis was performed on the records of 33 off-therapy parkinsonian patients. We analyzed the clinical score of three sequential upper limb movements: finger tapping, hand opening and closing, and forearm pronation and supination. The records showed that nearly all patients had difficulty in performing all three motor tasks, but movement scores showed that they found the sequential finger-tapping task significantly more difficult than the other two tasks. We suggest that parkinsonian patients find individual finger movements more difficult to execute than gross hand movements because--owing to their abnormal basal ganglia output--they lack the finer cortical control and greater facilitation that the finger task demands.
对33例停止治疗的帕金森病患者的记录进行了回顾性分析。我们分析了三个连续上肢动作的临床评分：手指敲击、手的开合以及前臂的旋前和旋后。记录显示，几乎所有患者在执行这三项运动任务时都有困难，但运动评分表明，他们发现连续的手指敲击任务比其他两项任务明显更难。我们认为，帕金森病患者发现单个手指动作比手部整体动作更难执行，原因是——由于其基底神经节输出异常——他们缺乏手指任务所需的更精细的皮层控制和更大的易化作用。
