Midorikawa Y, Kubota K, Mori M, Koyama H, Aihara N, Makuuchi M, Kajiura N
Second Department of Surgery, Faculty of Medicine, University of Tokyo, Japan.
Jpn J Clin Oncol. 1998 Mar;28(3):222-6. doi: 10.1093/jjco/28.3.222.
Diaphragmatic tumors, whether benign or malignant, may not generally reveal any symptoms in the early phase and may be found accidentally. During a pre-employment physical examination, a 20-year-old woman was found to have an abnormal shadow on the left diaphragm. An X-ray film, computed tomography and ultrasonography showed a giant mass on the left side, to the rear of the heart. She underwent surgery via a left thoraco-abdominal approach. The lesion was found to arise from the left diaphragm, and multiple disseminated lesions were scattered in the left thoracic cavity. Histological examination showed many large, oxyphilic rhabdoid cells between diffusely proliferating, spindle-shaped cells, and the tumor was subsequently diagnosed as a pleomorphic rhabdomyosarcoma of the diaphragm, of which the location and histological type were very rare. Despite adjuvant therapy, chest X-ray and CT revealed increasing tumor growth in the left cavity and she died one year after surgery.
膈肌肿瘤，无论良性还是恶性，早期通常可能不会出现任何症状，可能是偶然发现的。在一次入职前体检中，一名20岁女性被发现左侧膈肌有异常阴影。X线片、计算机断层扫描和超声检查显示心脏后方左侧有一个巨大肿块。她通过左胸腹联合入路接受了手术。发现病变起源于左侧膈肌，并且在左胸腔内散在多个播散性病变。组织学检查显示，在弥漫性增生的梭形细胞之间有许多大的嗜酸性横纹肌样细胞，该肿瘤随后被诊断为膈肌多形性横纹肌肉瘤，其发生部位和组织学类型非常罕见。尽管进行了辅助治疗，但胸部X线和CT显示左胸腔内肿瘤仍在生长，她在手术后一年去世。
