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特发性颅内高压患者视觉功能评估:一项前瞻性研究。

Assessment of visual function in idiopathic intracranial hypertension: a prospective study.

作者信息

Rowe F J, Sarkies N J

机构信息

Department of Orthoptics and Ophthalmology, Addenbrooke's NHS Trust, Cambridge, UK.

出版信息

Eye (Lond). 1998;12 ( Pt 1):111-8. doi: 10.1038/eye.1998.18.

Abstract

The visual function of 35 patients with a diagnosis of idiopathic intracranial hypertension was assessed prospectively over a 3 year period. In assessing the visual function of cases of idiopathic intracranial hypertension a number of tests were employed including visual field assessment with Humphrey and Goldmann perimeters and documentation of visual acuity and contrast sensitivity. Loss of visual function is the only serious complication and may occur early or late in the course of the condition. An appropriate and sensitive clinical assessment regime is therefore of importance in the outpatient situation. Visual field assessment was documented as the most sensitive to detection of visual loss, with statistically greater sensitivity in comparison with visual acuity and contrast sensitivity testing. Detection of asymptomatic visual loss indicates the necessity for visual monitoring to ensure detection of insidious visual loss. The types of visual field defects noted in this study were typical of anterior optic nerve pathology of raised intracranial pressure and commonly included arcuate defects, nasal steps and global constriction. Visual loss was noted at presentation and during follow-up in up to 87% of patients using Goldmann perimetry and up to 82% of patients using Humphrey perimetry. The visual status improved significantly throughout the follow-up period and the final visual outcome was excellent or good in 83% of patients.

摘要

对35例诊断为特发性颅内高压的患者的视觉功能进行了为期3年的前瞻性评估。在评估特发性颅内高压病例的视觉功能时,采用了多项测试,包括使用Humphrey视野计和Goldmann视野计进行视野评估,以及记录视力和对比敏感度。视觉功能丧失是唯一严重的并发症,可能在病情过程的早期或晚期出现。因此,在门诊情况下,合适且敏感的临床评估方案很重要。视野评估被证明对检测视力丧失最为敏感,与视力和对比敏感度测试相比,具有统计学上更高的敏感度。无症状视力丧失的检测表明需要进行视力监测,以确保发现隐匿性视力丧失。本研究中观察到的视野缺损类型是颅内压升高导致的前部视神经病变的典型表现通常包括弓形缺损、鼻侧阶梯和整体缩窄。使用Goldmann视野计检查时,高达87%的患者在就诊时和随访期间出现视力丧失;使用Humphrey视野计检查时,高达82%的患者出现视力丧失。在整个随访期间,视觉状态显著改善最终83%的患者视觉结局为优或良。

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