脑血容量的血流描记评估及其与颅内压变化的相关性

Rheographic assessment of cerebral blood volume and correlations with changes in intracranial pressure.

作者信息

Benabid A L, Persat J C, Piquard J F, Barge M, Chirossel J P

出版信息

Acta Neurochir (Wien). 1976;34(1-4):287-94. doi: 10.1007/BF01405887.

Abstract

The authors present a four electrode rheographic technique for simiquantitative continuous measurement of CBV, by examining changes in cerebral tissue impedance induced by changes in blood content of the brain parenchyma. Correlation between the data obtained and ICP measurements permits conclusions regarding the behaviour of the cerebral blood bed. pCO2 regulates CBV, and the phenomenon is reversible according to a hystereris shaped time course in acute experiments. The rebound of ICP after sudden injections of CSF into the cisterna magna is of a vasogenic nature. Changes in CSF volume induce contrary changes in CBV. Pharmacological effects can be studied. The validity of the method is discussed.

摘要

作者提出了一种四电极血流描记技术，用于通过检测脑实质血容量变化引起的脑组织阻抗变化来半定量连续测量脑血容量（CBV）。所获数据与颅内压（ICP）测量值之间的相关性有助于得出关于脑血床行为的结论。二氧化碳分压（pCO2）调节CBV，在急性实验中，该现象根据滞后形时间进程是可逆的。向枕大池突然注入脑脊液后颅内压的反弹具有血管源性。脑脊液体积的变化会引起CBV的相反变化。可以研究药物作用。并讨论了该方法的有效性。