Papadopoulou A L, Argiriou M, Bonoris M, Papadopoulos G S, Van Vliet-Constantinidou C, Stavrinadis C, Moschovi M, Tzortzatou-Stathopoulou F
First Department of Pediatrics, University of Athens, Aghia Sophia Children's Hospital, Greece.
Pediatr Hematol Oncol. 1998 May-Jun;15(3):265-9. doi: 10.3109/08880019809028795.
Anaplastic large cell lymphoma is a rare malignancy in childhood. We describe the case of a 6-year-old boy with Ki-1 lymphoma of the thymus who presented with an endocardiac mass. The first histologic analysis suggested a high-grade undifferentiated sarcoma, but reevaluation and immunohistochemistry confirmed the CD30+ lymphoid derivation of the process. The patient was given chemotherapy and 24 months later he remains in complete remission. It is noted that echocardiography was repeated many times to detect heart lesion.
间变性大细胞淋巴瘤是儿童期一种罕见的恶性肿瘤。我们描述了一名6岁患有胸腺Ki-1淋巴瘤并伴有心内膜肿块的男孩病例。首次组织学分析提示为高级别未分化肉瘤，但重新评估及免疫组化证实该病变起源于CD30+淋巴细胞。该患者接受了化疗，24个月后仍处于完全缓解状态。值得注意的是，多次重复超声心动图检查以检测心脏病变。
