Richer J P, Faure J P, Dugue T, Journe F, Bon D, Maillot N, Mothes D, Barbier J, Carretier M
Faculté de Médecine de Poitiers, Service de Chirurgie Viscérale, Hôpital J.-Bernard.
Chirurgie. 1997;122(8-9):491-5; discussion 496.
Multivisceral and orthotopic liver/small bowel transplantations have been performed to treat patients with intestinal failure associated with liver failure induced by parenteral nutrition. The aim of this experimental study was to determine the experimental liver-small bowel harvesting and transplantation technique that achieves the best compromise between liver and intestine ischemia times in pigs. Initial portal revascularization of the liver which reduces the hepatic warm ischemia time after cold ischemia preparation of the graft immersed in lactated ringer's solution at 4 degrees C, reduce the risk of primary non function of the graft.
已进行多脏器及原位肝/小肠移植以治疗因肠外营养导致肝衰竭相关的肠衰竭患者。本实验研究的目的是确定在猪身上能在肝和肠缺血时间之间取得最佳平衡的实验性肝小肠获取及移植技术。在4℃将移植物浸泡于乳酸林格液中进行冷缺血准备后，对肝脏进行初始门静脉血管重建可减少肝脏热缺血时间，降低移植物原发性无功能的风险。
