McGing P G
Biochemistry Department, Mater Misericordiae Hospital, Dublin.
Ir Med J. 1998 Mar-Apr;91(2):61-2.
Patterns of PSA requesting by General Practitioners were studied in one Dublin hospital for 11/1994-8/1995 and 11/1996-8/1997. 58% of requests (421/723) had PSA < 2ug/L and 82% had PSA < 4ug/L. Patients under 60 years accounted for 32% of the total requests but only 7% of these showed PSA levels over 4ug/L. PSA requests on these younger patients constitute a significant proportion of the PSA workload and yet appear to have low diagnostic yield. The mean age for all patients studied dropped from 68 years in 1994/1995 to 63 years in 1996/1997. This may reflect an increasing tendency to test all men over 50 years of age. This review of PSA requesting within our hospital's catchment area supports the view that PSA testing is not focused on higher risk individuals and shows tendencies towards a screening approach.
1994年11月至1995年8月以及1996年11月至1997年8月期间，在都柏林的一家医院对全科医生要求进行前列腺特异性抗原（PSA）检测的模式进行了研究。58%的检测要求（421/723）的PSA水平<2μg/L，82%的检测要求的PSA水平<4μg/L。60岁以下的患者占检测要求总数的32%，但其中只有7%的患者PSA水平超过4μg/L。对这些较年轻患者的PSA检测要求在PSA检测工作量中占很大比例，但诊断率似乎较低。所有研究患者的平均年龄从1994/1995年的68岁降至1996/1997年的63岁。这可能反映出对所有50岁以上男性进行检测的趋势在增加。对我院服务区域内PSA检测要求的这项审查支持了这样一种观点，即PSA检测并非针对高风险个体，而是呈现出筛查的倾向。
