Radev R
Akush Ginekol (Sofiia). 1997;36(3):21-3.
Fourteen women in labor with pregnancy of 39.1 +/- 1.1 gestational weeks and arterial hypertension (BSP of 183.4 +/- 12.4 and BDP of 90.6 +/- 14.3 mm Hg) were given chlopheline with a rate of infusion 0.0005, 0.001 mg/kg/hr for 120 min. Decrease of arterial pressure began at minute 15.7 +/- 0.3 after starting perfusion, and the hypotensive effect lasted for 300 minutes. At minute 360, a new dose of chlopheline was needed. Against the background of arterial hypertension, a decrease of BSP, BDP and P was observed, and the central hemodynamics remained unchanged within statistically reliable range. The changes observed in the hemodynamics did not affect labor activity and the fetus. The analgesic effect of chlopheline was favorable. Perfusion of chlopheline at a rate of infusion 0.0005, 0.001 mg/kg/hr is a choice to provide a bulk of positive hypotensive and analgesic affect on the woman in labor.
十四名孕周为39.1±1.1周且患有动脉高血压（收缩压为183.4±12.4，舒张压为90.6±14.3毫米汞柱）的临产妇女以0.0005、0.001毫克/千克/小时的输注速率给予氯菲林，持续120分钟。灌注开始后15.7±0.3分钟动脉压开始下降，降压作用持续300分钟。在360分钟时，需要新的一剂氯菲林。在动脉高血压背景下，观察到收缩压、舒张压和脉压下降，且中心血流动力学在统计学可靠范围内保持不变。血流动力学的变化未影响产程和胎儿。氯菲林的镇痛效果良好。以0.0005、0.001毫克/千克/小时的输注速率灌注氯菲林是为临产妇女提供大量积极降压和镇痛作用的一种选择。
