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65岁以上高血压性壳核出血患者的手术结果

Surgical outcome of hypertensive putaminal hemorrhage in patients older than 65 years.

作者信息

Lin C L, Howng S L

机构信息

Department of Neurosurgery, Kaohsiung Medical College Hospital, Taiwan, Republic of China.

出版信息

Kaohsiung J Med Sci. 1998 May;14(5):280-5.

PMID:9619013
Abstract

There is no consensus of opinion on the treatment of hypertensive putaminal hemorrhage (HPH), especially in patients older than 65 years. The purpose of this study was to study the surgical outcome of HPH in patients older than 65 years while considering mortality and activity of daily life. Among eighty-three patients aged 65 or older with HPH, fifty-one patients received only medical treatment and 32 were operated upon to remove the hematoma. Each patient was measured by the intracerebral hemorrhage-intracranial hemorrhage grading scale (ICH Grade) which used the sum of eye opening and motor response scores derived from Glasgow Coma Scale. The cubic content of the HPH was calculated from measurement of maximum width (X), length (Y) and height (Z), and the hematoma volume taken as 1/2 that volume (X. Y. Z/2). The acute mortality in surgically treated group was 40.6% and three patients died during the follow-up period from one to six months after the operation. Determinant for the prognosis was the ICH grade and the volume of the hematoma. Patients who returned to ADL 1 and 2 (good recovery) after surgical treatment were 40.0% in ICH Grade I, 16.7% in ICH Grade II, and 20.0% in ICH Grade III. Among those patients who were in ICH Grade IV, none had good recovery. The acute mortality was zero in ICH Grade I, 16.7% in ICH Grade II, 40.0% in ICH Grade III, and 62.5% in ICH Grade IV. The crucial size was 60 ml with a mortality of 77.8% for hematomas larger and 39.1% for hematomas smaller than that. From our lim ited experience, we learned that operation in elderly patients with HPH was considered only in patients with hematomas between 20 to 60 ml, with a high operative mortality and only one-fourth having a good recovery postoperatively.

摘要

对于高血压性壳核出血(HPH)的治疗,尤其是65岁以上患者的治疗,目前尚无共识。本研究的目的是研究65岁以上HPH患者的手术结果,同时考虑死亡率和日常生活活动能力。在83例65岁及以上的HPH患者中,51例仅接受药物治疗,32例接受了血肿清除手术。采用脑出血-颅内出血分级量表(ICH分级)对每位患者进行评估,该量表使用格拉斯哥昏迷量表得出的睁眼和运动反应评分之和。通过测量HPH的最大宽度(X)、长度(Y)和高度(Z)来计算其立方体积,血肿体积取该体积的1/2(X·Y·Z/2)。手术治疗组的急性死亡率为40.6%,3例患者在术后1至6个月的随访期内死亡。预后的决定因素是ICH分级和血肿体积。手术治疗后恢复到日常生活活动能力1级和2级(良好恢复)的患者,在ICH I级中为40.0%,在ICH II级中为16.7%,在ICH III级中为20.0%。在ICH IV级的患者中,无人恢复良好。ICH I级的急性死亡率为零,ICH II级为16.7%,ICH III级为40.0%,ICH IV级为62.5%。关键体积为60毫升,血肿大于该体积时死亡率为77.8%,小于该体积时死亡率为39.1%。根据我们有限的经验,我们了解到,老年HPH患者仅在血肿体积为20至60毫升时考虑手术,手术死亡率高,术后仅有四分之一的患者恢复良好。

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