Manini C, Pietribiasi F, Sapino A, Donadio S
Servizio di Anatomia Patologica, Ospedale Santa Croce, U.S.L.8, Moncalieri, TO.
Pathologica. 1998 Apr;90(2):152-5.
Metastasis to the breast from extramammary malignancies are rare especially from ovarian carcinoma. We report a case of a 72-year-old woman with a mass in the right ovary and a lump in the left breast together with axillary lymph node enlargement. Both the ovarian and mammary neoplasms were found to be papillary carcinoma with similar immunohistochemical pattern (anti-CA-125: positive; anti-GCDFP-15: negative); some of the axillary lymph nodes showed metastasis with papillary features. On the basis of clinical, morphological and immunohistochemical data we proposed the diagnosis of papillary cystoadenocarcinoma of the ovary with simultaneous metastasis to the breast and axillary lymph nodes.
乳腺外恶性肿瘤转移至乳腺非常罕见，尤其是来自卵巢癌的转移。我们报告一例72岁女性，其右卵巢有肿物，左乳腺有肿块，同时伴有腋窝淋巴结肿大。卵巢和乳腺肿瘤均为乳头状癌，具有相似的免疫组化模式（抗CA - 125：阳性；抗GCDFP - 15：阴性）；部分腋窝淋巴结显示有乳头状特征的转移。基于临床、形态学和免疫组化数据，我们诊断为卵巢乳头状囊腺癌同时转移至乳腺和腋窝淋巴结。
