Kim Y B, Ghosh K, Ainbinder S, Berek J S
Department of Obstetrics and Gynecology, UCLA School of Medicine 90024, USA.
Cancer Treat Res. 1998;95:253-76. doi: 10.1007/978-1-4615-5447-9_9.
Endometrial carcinoma is associated with a good prognosis because patients tend to present with early disease. Mass screening is therefore unlikely to be of benefit. High-risk populations may benefit from screening, but no prospective studies have demonstrated a benefit in any population. The most promising modality for screening appears to be TVS, and a normal TVS may also preclude the need for further evaluation of symptomatic patients. The appropriate use of TVS in patients on tamoxifen is currently unknown. Hysteroscopy and endometrial biopsy may have a role in the evaluation of symptomatic patients but do not appear promising as screening modalities.
子宫内膜癌预后良好，因为患者往往表现为疾病早期。因此，大规模筛查不太可能有益。高危人群可能从筛查中获益，但尚无前瞻性研究表明对任何人群都有益。最有前景的筛查方式似乎是经阴道超声（TVS），正常的TVS也可能避免对有症状患者进行进一步评估。目前尚不清楚在服用他莫昔芬的患者中TVS的恰当应用。宫腔镜检查和子宫内膜活检可能在有症状患者的评估中发挥作用，但作为筛查方式似乎前景不佳。
