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[β-胡萝卜素和易善复在脂质代谢紊乱中的免疫调节和抗氧化作用]

[The immunomodulating and antioxidant action of beta-carotene and essentiale in a lipid metabolic disorder].

作者信息

Uteshev B S, Baĭburin F Ia, Prokopenko L G

机构信息

Department of Pharmacology, Russian State Medical University, Moscow, Russia.

出版信息

Eksp Klin Farmakol. 1998 Mar-Apr;61(2):41-4.

PMID:9621173
Abstract

Excessive supply of lipids to the organism of rats causes increase in lipid peroxidation, reduction of red cell energy status, the appearance in them of immunosuppressive properties, and inhibition of immunological reactivity. Administration of beta-carotene and essential corrects the biochemical status and immunological reactivity of the organism in alimentary lipid loading. beta-Carotene cancels the immunosuppressive properties of light red blood cells, whereas essential induces the appearance of immunostimulating properties in the heavy cells.

摘要

给大鼠机体过量供应脂质会导致脂质过氧化增加、红细胞能量状态降低、出现免疫抑制特性以及免疫反应性受到抑制。给予β-胡萝卜素和必需物质可纠正饮食性脂质负荷时机体的生化状态和免疫反应性。β-胡萝卜素消除了浅红细胞的免疫抑制特性,而必需物质则使重细胞出现免疫刺激特性。

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