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[成人原发性肺结核的实验室诊断方法]

[Laboratory diagnostic methods in primary pulmonary tuberculosis in adults].

作者信息

Sakhelashvili M I, Platonova I L, Lapovets' N Ie, Kapral' O Ia, Kiromasova N I, Mazhak K D, Chura H Ie, Vdovenko O V, Pobiehushchyĭ M M

出版信息

Lik Sprava. 1998 Jan-Feb(1):95-9.

PMID:9621627
Abstract

A comprehensive clinical and roentgenological evaluation was done in 495 patients with primary tuberculosis aged more than eighteen. The clinical pattern of primary forms of the specific process was characterized by predominance of tuberculosis of intrathoracic lymph nodes (tumorous form) infiltrative tuberculosis of pararoot or lower-lobe localization, and exudative pleurisy. Primary tuberculosis was diagnosed in 56.4% of adults. Examination of sputum for changed forms of MBT increases the frequency of verification of diagnosis by 16.0% in comparison with conventional microbiological assays. Primary tuberculosis of the respiratory system in 63.5% of adults runs its course against the background of significant disorders of T- and B-systems of lymphocytes, antituberculous immune defence and bodily metabolic processes. The use of a complex of immunologic studies was found to promote the accuracy of diagnosis of primary tuberculosis from 56.4% up to 79.6%, that of biochemical ones-from 56.4% to 77.5%.

摘要

对495例18岁以上原发性肺结核患者进行了全面的临床和X线检查。特异性病变原发性形式的临床模式特点为胸内淋巴结结核(肿瘤型)、根周或下叶浸润性结核以及渗出性胸膜炎占优势。56.4%的成年人被诊断为原发性肺结核。与传统微生物检测方法相比,对痰液中结核分枝杆菌形态变化的检查使诊断核实频率提高了16.0%。63.5%的成年呼吸系统原发性肺结核在T和B淋巴细胞系统、抗结核免疫防御及身体代谢过程存在明显紊乱的背景下发病。发现采用一系列免疫学研究可使原发性肺结核诊断的准确率从56.4%提高到79.6%,生化研究的准确率从56.4%提高到77.5%。

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