Matiash V I
Lik Sprava. 1998 Jan-Feb(1):156-8.
The clinical course of grave forms of leptospirosis presents with disorders in the fluid and electrolyte balance and acid-base condition (ABC) which fact necessitates taking prompt action for the condition to be corrected. Correction of disorders in the fluid and electrolyte balance involves employment of glucose and salt solutions, dextrans, and in most severe cases albumin drugs under control of hematocrit values, plasma osmolarity, and 24-h diuresis monitoring. Correction of disorders in the ABC is primarily aimed at alleviating the metabolic acidosis through detoxication by applying specific therapy together with oral and parenteral administration of sodium hydrogen carbonate.
重症钩端螺旋体病的临床病程表现为液体和电解质平衡以及酸碱状态（ABC）紊乱，这一情况需要迅速采取行动来纠正该状况。纠正液体和电解质平衡紊乱涉及使用葡萄糖和盐溶液、右旋糖酐，在最严重的情况下，在血细胞比容值、血浆渗透压和24小时尿量监测的控制下使用白蛋白药物。纠正ABC紊乱主要旨在通过应用特定疗法以及口服和胃肠外给予碳酸氢钠进行解毒来减轻代谢性酸中毒。
