Reichenbach J R, Feiwell R, Kuppusamy K, Bahn M, Haacke E M
Mallinckrodt Institute of Radiology, Washington University, School of Medicine, St. Louis, MO, USA.
Magn Reson Imaging. 1998 Apr;16(3):281-7. doi: 10.1016/s0730-725x(97)00276-2.
Activation of cortical and subcortical motor areas of the brain, including primary motor cortex, supplementary motor area, basal ganglia and cerebellum, were successfully investigated in seven right-handed, normal volunteers during a simple, rapid, thumb flexion-extension task using functional magnetic resonance imaging. A multi-slice echo-planar imaging sequence was used to cover the entire brain. A signal increase varying from 2% to 6% was observed for the different regions involved in the motor task. Moving the non-dominant thumb was associated with a more bilateral activation pattern in both putamen and cerebellar regions. This study demonstrates the capability of functional magnetic resonance imaging to delineate simultaneously many activated brain areas that are commonly thought to be involved in the performance of motor tasks.
在一项简单、快速的拇指屈伸任务中，利用功能磁共振成像技术，成功对7名右利手正常志愿者大脑的皮质和皮质下运动区域（包括初级运动皮层、辅助运动区、基底神经节和小脑）的激活情况进行了研究。采用多层回波平面成像序列覆盖整个大脑。在参与运动任务的不同区域观察到信号增强幅度在2%至6%之间。移动非优势手拇指时，壳核和小脑区域的激活模式更具双侧性。这项研究证明了功能磁共振成像技术能够同时描绘出许多通常被认为参与运动任务执行的激活脑区。
