Kodama H, Sato G, Mikami T
Am J Vet Res. 1976 Sep;37(9):1091-4.
The phagocytic and bactericidal activities to Salmonella pullorum (strain 9-25) or Salmonella senftenberg (strain 99D) were examined in chicken splenic phagocytes from 0-day-old to 2-month-old chickens. The phagocytic activity against S pullorum increased in splenic phagocytes from chickens older than 7 days, but significant changes in activity against S senftenberg were not observed during the experimental period. The bactericidal activity of splenic phagocytes against S senftenberg was higher than that of phagocytes against S pullorum during the same period. Increase of the bactericidal activity against S pullorum was observed with increasing age, but the activity of the splenic phagocytes from 0-day-old chickens against S senftenberg was similar to that of the phagocytes from 2-month-old chickens. Although delayed hypersensitivity was confirmed by delayed wattle reaction in 2-month-old chickens sensitized with living S pullorum, the sensitization did not markedly affect phagocytic and bactericidal activities.
检测了0日龄至2月龄鸡脾脏吞噬细胞对鸡白痢沙门氏菌（9-25株）或肠炎沙门氏菌（99D株）的吞噬和杀菌活性。7日龄以上鸡的脾脏吞噬细胞对鸡白痢沙门氏菌的吞噬活性增加，但在实验期间未观察到对肠炎沙门氏菌活性的显著变化。同期脾脏吞噬细胞对肠炎沙门氏菌的杀菌活性高于对鸡白痢沙门氏菌的杀菌活性。随着年龄增长，观察到对鸡白痢沙门氏菌的杀菌活性增加，但0日龄鸡的脾脏吞噬细胞对肠炎沙门氏菌的活性与2月龄鸡的吞噬细胞活性相似。尽管在用活鸡白痢沙门氏菌致敏的2月龄鸡中通过肉垂迟发型反应证实了迟发型超敏反应，但致敏并未显著影响吞噬和杀菌活性。
