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[克罗恩病中的胃十二指肠受累及局限性肠狭窄]

[Gastroduodenal involvement and circumscribed intestinal stricture in Crohn disease].

作者信息

Makowiec F, Starlinger M

机构信息

Abteilung für Chirurgie, Landeskrankenhaus Klagenfurt.

出版信息

Zentralbl Chir. 1998;123(4):338-43.

PMID:9622891
Abstract

Symptomatic gastroduodenal Crohn's disease (CD) is rare although new endoscopic/histologic data indicate a typical focally enhanced gastritis in up to half of all patients with CD. One third of the patients with symptomatic gastroduodenal CD undergo surgery, most of them for (gastro-) duodenal obstruction. Gastroenterostomy with vagotomy is the surgical treatment of choice. Resection, strictureplasty or balloon dilatation can be performed in selected patients. Enterogastric and enteroduodenal fistulas are rare, frequently missed during routine examination and often detected only during laparotomy. Treatment of those fistulas consists of resection of distal bowel (fistula origin) with suture closure of the fistula opening in the stomach/duodenum. Recurrence rate after surgery for gastroduodenal CD is lower than in ileal and/or colonic disease, and only a minority of the patients requires further surgical intervention. Bowel obstruction is a frequent indication for surgery in CD. Interventional or surgical therapy should be performed in chronic-recurrent obstruction, progressive stenosis and stenosis refractory to medical treatment. In short fibrous stenosis of the small bowel or ileocecal anastomosis without acute inflammation or perforating complications balloon dilatation or, if endoscopic access is not possible, strictureplasty should be performed. In all other cases, especially in colonic strictures with their increased risk of malignancy, resection is the treatment of choice. The results of balloon dilatation, strictureplasty or resection are comparable with five year reoperation rates reported between 20% and 38%.

摘要

有症状的胃十二指肠克罗恩病(CD)较为罕见,尽管新的内镜/组织学数据表明,在所有CD患者中,多达一半存在典型的局灶性强化胃炎。三分之一有症状的胃十二指肠CD患者接受手术治疗,其中大多数是因为(胃-)十二指肠梗阻。胃迷走神经切断术式胃肠吻合术是首选的手术治疗方法。在特定患者中可进行切除术、狭窄成形术或球囊扩张术。胃小肠和十二指肠瘘很少见,在常规检查中常被漏诊,通常仅在剖腹手术时才被发现。这些瘘的治疗包括切除远端肠段(瘘的起源部位),并缝合胃/十二指肠处的瘘口。胃十二指肠CD手术后的复发率低于回肠和/或结肠疾病,只有少数患者需要进一步的手术干预。肠梗阻是CD患者常见的手术指征。对于慢性复发性梗阻、进行性狭窄以及药物治疗无效的狭窄,应进行介入或手术治疗。对于无急性炎症或穿孔并发症的小肠短纤维性狭窄或回盲部吻合口狭窄,应进行球囊扩张术,若无法进行内镜操作,则应进行狭窄成形术。在所有其他情况下,尤其是在结肠癌风险增加的结肠狭窄病例中,切除术是首选治疗方法。球囊扩张术、狭窄成形术或切除术的效果相当,五年再次手术率在20%至38%之间。

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