Suppr超能文献

[肠道手术治疗克罗恩病小肠狭窄]

[Intestinal surgery in the treatment of stenoses of the small intestine in Crohn disease].

作者信息

Quandalle P, Gambiez L, Colombel J F, Paris J C, Cortot A

机构信息

Clinique Chirurgicale Ouest, CHRU, Lille.

出版信息

Gastroenterol Clin Biol. 1994;18(2):151-6.

PMID:8013797
Abstract

Strictureplasty is an alternative to extensive and/or multiple small bowel resections in the surgical treatment of Crohn's disease. We here report a series of 22 patients (12 M-10 F--mean age years: 28). All patients had a non-perforative form of Crohn's disease lasting for a mean of 8 years. Nine out of 22 had had previous intestinal resection. A total of 201 stenosis was identified during peroperative examination (mean per patient: 9). Only tight stenoses (diameter < 2 cms) were treated while others were left untouched (n = 22 in 11 patients). Eighty-three stenoses were treated by short strictureplasty and 24 by long strictureplasty using steel thread. One or several resections were simultaneously performed in 15 patients. Mortality was nil. A post operative abscess without loosened suture was drained. The mean follow-up in the 22 patients was 24 months (3-7 years). Clinical and radiological symptoms of stenosis were relieved after strictureplasty. Clinical recurrence occurred in 5 patients among 12 followed-up more than 2 years. Subsequent surgery was required in 4: in one case hemorrhagic ulceration developed within a long strictureplasty and in 3 others stenosis developed in plasty areas but also in previously healthy areas. In conclusion, strictureplasty is a short and long-term efficient procedure in the treatment of Crohn's disease stenosis. It allows limiting extensive intestinal resection. A more prolonged follow-up is needed in order to evaluate the rate of long-term recurrence and complications that would limit the interest of this technique.

摘要

狭窄成形术是克罗恩病外科治疗中广泛和/或多次小肠切除的替代方法。我们在此报告一组22例患者(男性12例,女性10例,平均年龄28岁)。所有患者均为非穿孔型克罗恩病,病程平均8年。22例中有9例曾接受过肠道切除术。术中检查共发现201处狭窄(平均每位患者9处)。仅治疗狭窄严重的部位(直径<2厘米),其他部位未处理(11例患者共22处)。83处狭窄采用短段狭窄成形术治疗,24处采用钢丝长段狭窄成形术治疗。15例患者同时进行了一次或多次切除术。无死亡病例。术后有1例脓肿,未出现缝线松动,已引流。22例患者的平均随访时间为24个月(3 - 7年)。狭窄成形术后,狭窄的临床和放射学症状得到缓解。在随访超过2年的12例患者中,5例出现临床复发。4例需要再次手术:1例在长段狭窄成形术部位出现出血性溃疡,另外3例在成形部位及先前健康的部位出现狭窄。总之,狭窄成形术是治疗克罗恩病狭窄的一种短期和长期有效的方法。它可以减少广泛的肠切除。需要更长时间的随访来评估长期复发率和并发症发生率,这些可能会限制该技术应用的价值。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验