Falcini F, Bardare M, Cimaz R, Lippi A, Corona F
Department of Paediatrics, University of Florence, Italy.
Arch Dis Child. 1998 Apr;78(4):367-70. doi: 10.1136/adc.78.4.367.
Leukaemia can present with joint swelling in the absence of abnormal haematological findings. Arthritis as a presenting sign of lymphoma, however, is extremely rare. Three children with non-Hodgkin's lymphoma who had joint swelling at the onset of their disease are reported. Two cases showed histological features of anaplastic large cell lymphoma (Ki-1/CD30 positive), and one of angioimmunoblastic T cell lymphoma. In all patients the unusual presentation delayed correct diagnosis.
白血病可在血液学检查结果无异常的情况下出现关节肿胀。然而,关节炎作为淋巴瘤的首发症状极为罕见。本文报告了3例非霍奇金淋巴瘤患儿,他们在疾病发作时出现关节肿胀。2例显示间变性大细胞淋巴瘤(Ki-1/CD30阳性)的组织学特征,1例为血管免疫母细胞性T细胞淋巴瘤。所有患者这种不寻常的表现均延误了正确诊断。