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关节炎作为非霍奇金淋巴瘤的首发症状。

Arthritis as a presenting feature of non-Hodgkin's lymphoma.

作者信息

Falcini F, Bardare M, Cimaz R, Lippi A, Corona F

机构信息

Department of Paediatrics, University of Florence, Italy.

出版信息

Arch Dis Child. 1998 Apr;78(4):367-70. doi: 10.1136/adc.78.4.367.

Abstract

Leukaemia can present with joint swelling in the absence of abnormal haematological findings. Arthritis as a presenting sign of lymphoma, however, is extremely rare. Three children with non-Hodgkin's lymphoma who had joint swelling at the onset of their disease are reported. Two cases showed histological features of anaplastic large cell lymphoma (Ki-1/CD30 positive), and one of angioimmunoblastic T cell lymphoma. In all patients the unusual presentation delayed correct diagnosis.

摘要

白血病可在血液学检查结果无异常的情况下出现关节肿胀。然而,关节炎作为淋巴瘤的首发症状极为罕见。本文报告了3例非霍奇金淋巴瘤患儿,他们在疾病发作时出现关节肿胀。2例显示间变性大细胞淋巴瘤(Ki-1/CD30阳性)的组织学特征,1例为血管免疫母细胞性T细胞淋巴瘤。所有患者这种不寻常的表现均延误了正确诊断。

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本文引用的文献

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Clinical features and treatment outcome for children with CD30+ large-cell non-Hodgkin's lymphoma.
J Clin Oncol. 1994 May;12(5):895-8. doi: 10.1200/JCO.1994.12.5.895.
6
Non-Hodgkin's lymphoma presenting as polyarthritis.表现为多关节炎的非霍奇金淋巴瘤
Br J Rheumatol. 1994 Jan;33(1):79-84. doi: 10.1093/rheumatology/33.1.79.
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Monocyte/macrophage system and malignancies.单核细胞/巨噬细胞系统与恶性肿瘤
Med Pediatr Oncol. 1994;23(5):444-51. doi: 10.1002/mpo.2950230510.
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Leukemic arthritis.白血病性关节炎
Semin Arthritis Rheum. 1994 Aug;24(1):48-56. doi: 10.1016/0049-0172(94)90099-x.
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Non-Hodgkin's lymphoma and polyarthritis.非霍奇金淋巴瘤与多关节炎。
Br J Rheumatol. 1995 Mar;34(3):293. doi: 10.1093/rheumatology/34.3.293.

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