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基底细胞上皮瘤(BCE)中的多巴阳性细胞和黑色素

Dopa-positive cells and melanin in basal cell epithelioma (BCE).

作者信息

Deppe R, Pullmann H, Steigleder G K

出版信息

Arch Dermatol Res (1975). 1976 Jul 26;256(1):79-83. doi: 10.1007/BF00561183.

DOI:10.1007/BF00561183
PMID:962384
Abstract

In 47 out of 61 bce's, melanocytes were detectable with the aid of Dopa-reaction. In 24 of these cases, the percentage of tumour cells was less 5%, and in 23 it was more. The melanocytes preferred the periphery of the epithelial tumour formations. Only when the proportion of melanocytes exceeded 5% were they also to be found in the central parts of the tumours. Generally the melanocytes were more numerous in the upper parts of tumours, next to the epidermis. Our findings strengthen the opinion, that bce is a tumour of the primary hair germ.

摘要

在61例基底细胞上皮瘤(bce)中,有47例借助多巴反应可检测到黑素细胞。在其中24例中,肿瘤细胞百分比小于5%,23例中则大于5%。黑素细胞倾向于在上皮性肿瘤结构的周边。仅当黑素细胞比例超过5%时,才会在肿瘤中央部分发现它们。一般来说,黑素细胞在肿瘤上部、紧邻表皮处数量更多。我们的发现支持了这样一种观点,即基底细胞上皮瘤是原发毛胚的肿瘤。

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Dopa-positive cells and melanin in basal cell epithelioma (BCE).基底细胞上皮瘤(BCE)中的多巴阳性细胞和黑色素
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2
Cells with positive Dopa--reaction in the infiltrate of basal cell epithelioma (bce).
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引用本文的文献

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Turk J Med Sci. 2022 Jun;52(3):691-698. doi: 10.55730/1300-0144.5362. Epub 2022 Jun 16.
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Molecular Mechanisms and Targeted Therapies of Advanced Basal Cell Carcinoma.晚期基底细胞癌的分子机制和靶向治疗。
Int J Mol Sci. 2022 Oct 8;23(19):11968. doi: 10.3390/ijms231911968.
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Pigmented Basal Cell Carcinoma Masquerading as a Melanoma.伪装成黑色素瘤的色素性基底细胞癌

本文引用的文献

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Pigmented calcifying epithelioma. Review and presentation of a case with unusual features.色素性钙化上皮瘤。一例具有不寻常特征病例的回顾与展示。
Arch Dermatol. 1974 Nov;110(5):773-4. doi: 10.1001/archderm.110.5.773.
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Pigmented basal cell epithelioma. Light and electron microscopic studies on tumours and cell cultures.色素性基底细胞上皮瘤。肿瘤及细胞培养的光镜和电镜研究。
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