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同种异体移植物联合生物可吸收膜与异体/同种异体复合移植物联合生物可吸收膜的临床评估。100例连续治疗病例。

A clinical evaluation of an allograft combined with a bioabsorbable membrane versus an alloplast/allograft composite graft combined with a bioabsorbable membrane. 100 consecutively treated cases.

作者信息

Harris R J

出版信息

J Periodontol. 1998 May;69(5):536-46. doi: 10.1902/jop.1998.69.5.536.

DOI:10.1902/jop.1998.69.5.536
PMID:9623896
Abstract

The purpose of this study was to evaluate and compare the clinical effectiveness of 2 surgical techniques in treating periodontal defects. Both techniques involved tetracycline treatment of a root planed root, grafting the osseous defect with a bone graft, and placement of a bioabsorbable membrane. In group A, the bone graft was a mix of demineralized freeze-dried allograft, tetracycline, and porous hydroxyapatite and in group B, the bone graft was a mix of demineralized freeze-dried allograft and tetracycline. There was a statistically significant increase in recession (group A, 0.7 mm; group B, 0.6 mm), decreases in probing depth (group A, 6.1 mm; group B, 5.6 mm), and gains in attachment levels (group A, 5.4 mm; group B, 5.0 mm). There were no statistically significant differences between the results for either group. The defects associated with furcations and those that were not associated with furcations had similar results, except for the percent attachment gain. Smoking and age (> or =60 years old) could not be associated with results. Defects with > or =10 mm probing depths (PD) had greater PD reductions (group A, 7.7 mm; group B, 7.1) and attachment gains (group A, 6.6 mm; group B, 6.4 mm) than the defects with probing depths less than 10 mm (probing reduction group A, 4.8 mm; group B, 4.5 mm; attachment gain group A, 4.4 mm; group B, 4.0 mm). Both surgical procedures improved the clinical situation. However, neither technique seemed to offer a statistical advantage over the other. The inclusion of porous hydroxyapatite did not improve or diminish the results.

摘要

本研究的目的是评估和比较两种手术技术治疗牙周缺损的临床疗效。两种技术均包括对根面平整后的牙根进行四环素处理、用骨移植材料填充骨缺损以及放置生物可吸收膜。A组的骨移植材料是脱矿冻干同种异体骨、四环素和多孔羟基磷灰石的混合物,B组的骨移植材料是脱矿冻干同种异体骨和四环素的混合物。退缩有统计学意义的增加(A组为0.7毫米;B组为0.6毫米),探诊深度降低(A组为6.1毫米;B组为5.6毫米),附着水平增加(A组为5.4毫米;B组为5.0毫米)。两组结果之间无统计学显著差异。与根分叉相关的缺损和与根分叉无关的缺损结果相似,但附着增加百分比除外。吸烟和年龄(≥60岁)与结果无关。探诊深度≥10毫米(PD)的缺损比探诊深度小于10毫米的缺损有更大的探诊深度降低(A组为7.7毫米;B组为7.1毫米)和附着增加(A组为6.6毫米;B组为6.4毫米)(探诊深度降低A组为4.8毫米;B组为4.5毫米;附着增加A组为4.4毫米;B组为4.0毫米)。两种手术方法均改善了临床状况。然而,两种技术似乎都没有统计学上优于对方的优势。加入多孔羟基磷灰石并未改善或降低结果。

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