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治疗性门腔分流术和脾肾分流术的风险。

Risks in therapeutic portacaval and splenorenal shunts.

作者信息

Malt R A, Szczerban J, Malt R B

出版信息

Ann Surg. 1976 Sep;184(3):279-88. doi: 10.1097/00000658-197609000-00005.

Abstract

Analyses of the records of 120 patients who underwent portacaval shunting (PCS, 57%) or splenorenal shunting (SRS, 43%) from 1966-1973 disclosed that patients in each group undergoing elective shunts had the same preoperative physical condition and postoperative mortality rates (approximately 20%). Although the post-operative death rate from emergency shunts was 48%, patients having these procedures were poorer risks. Long-term incidences of encephalopathy were the same, irrespective of the type of shunt (PCS, 46%; SRS 36%, P greater than 0.5). Despite comparisons of data most unfavorable for PCS, 5-year survival rates were also the same after either type of shunt (all PCS, 29 +/- 7.5%, SRS, 42.0 +/- 7.4%, P = 0.23). The survival rate after elective PCS was also the same as after SRS during the entire 5-year period. However, the survival after all elective PCS and SRS was significantly greater than after emergency PCS (P range = 0.005-0.038); the poorer results of emergency shunting could be partly attributed to the poorer condition of patients selected. A numerical score based on serum bilirubin concentrations, ascites, and urgency of shunting reliably predicts postoperative mortality. Long-term encephalopathy is predicted by a history of encephalopathy and the urgency of shunting.

摘要

对1966年至1973年间接受门腔分流术(PCS,57%)或脾肾分流术(SRS,43%)的120例患者的记录分析显示,每组接受择期分流术的患者术前身体状况和术后死亡率相同(约20%)。尽管急诊分流术后的死亡率为48%,但接受这些手术的患者风险更高。无论分流类型如何,脑病的长期发生率相同(PCS为46%;SRS为36%,P>0.5)。尽管对PCS最不利的数据进行了比较,但两种分流术后的5年生存率也相同(所有PCS为29±7.5%,SRS为42.0±7.4%,P=0.23)。在整个5年期间,择期PCS后的生存率也与SRS后的生存率相同。然而,所有择期PCS和SRS后的生存率显著高于急诊PCS后的生存率(P范围=0.005 - 0.038);急诊分流术结果较差部分可归因于所选患者的病情较差。基于血清胆红素浓度、腹水和分流紧迫性的数值评分可可靠预测术后死亡率。脑病病史和分流紧迫性可预测长期脑病。

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