Szlatenyi C S, Capes K F, Wang R Y
Division of Emergency Medicine, Brown University School of Medicine, Providence, RI, USA.
Ann Emerg Med. 1998 Jun;31(6):773-6. doi: 10.1016/s0196-0644(98)70240-9.
This is the first report to describe the delayed onset of hypoglycemia in a child after ingestion of one tablet of glipizide. A 2-year-old boy was observed to ingest 5 mg glipizide and 25 mg hydrochlorothiazide. Activated charcoal was administered within 35 minutes of ingestion. Hypoglycemia (serum glucose 49 mg/dL) developed 11 hours later. Emergency physicians must be aware of the potential for delayed hypoglycemia in children with single-tablet ingestions of glipizide. Prolonged monitoring of glucose levels is warranted.
这是第一份描述儿童服用一片格列吡嗪后低血糖延迟发作的报告。一名2岁男孩被观察到摄入了5毫克格列吡嗪和25毫克氢氯噻嗪。摄入后35分钟内给予了活性炭。11小时后出现低血糖（血清葡萄糖49毫克/分升）。急诊医生必须意识到儿童单次摄入格列吡嗪后有发生延迟性低血糖的可能性。有必要对血糖水平进行长时间监测。
