大鼠垂体前叶腺细胞之间的突触样接触。
Synaptoid contacts between gland cells of the anterior pituitary of the rat.
作者信息
Liu Y Y, Ju G
机构信息
Department of Ultrastructural Research, Fourth Military Medical University, Xi'an, PR China.
出版信息
Anat Rec. 1998 Jun;251(2):181-4. doi: 10.1002/(SICI)1097-0185(199806)251:2<181::AID-AR5>3.0.CO;2-1.
BACKGROUND
There is evidence suggesting cross-talk among gland cells of the anterior pituitary. We had reported a rare form of synaptoid contact between corticotrophs in the anterior pituitary of the dog. We then found similar synaptoid contacts with different characteristics in the rat, as described in the present article.
METHODS
Male Sprague-Dawley rats were used. The anterior pituitaries were prepared for ultrastructural study of substance P immunoreactivity of the anterior pituitary. Routine preembedding immunohistochemical staining was conducted, the sections were embedded in Epon 812 (Serva Feinbiochemica, Heidelberg, New York), and ultrathin sections were prepared.
RESULTS
In the anterior pituitary of the rat, synaptoid contacts were found between corticotrophs and lactotrophs. They appeared very close to typical synapses in the central nervous system, aside from evident weakness of presynaptic density.
CONCLUSIONS
The presence of synaptoid contacts suggests a form of cross-talk between the gland cells in the anterior pituitary of the rat.
背景
有证据表明垂体前叶腺细胞之间存在相互作用。我们曾报道过犬垂体前叶促肾上腺皮质激素细胞之间一种罕见的类突触接触形式。如本文所述，随后我们在大鼠中发现了具有不同特征的类似类突触接触。
方法
使用雄性Sprague-Dawley大鼠。制备垂体前叶用于垂体前叶P物质免疫反应性的超微结构研究。进行常规包埋前免疫组织化学染色，将切片包埋于Epon 812（Serva Feinbiochemica，海德堡，纽约）中，并制备超薄切片。
结果
在大鼠垂体前叶中，发现促肾上腺皮质激素细胞与催乳激素细胞之间存在类突触接触。除了突触前密度明显减弱外，它们看起来与中枢神经系统中的典型突触非常相似。
结论
类突触接触的存在表明大鼠垂体前叶腺细胞之间存在一种相互作用形式。
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