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急诊室中的样本选择偏倚:酒精在损伤中的作用研究

Sample selection bias in the emergency room: an examination of the role of alcohol in injury.

作者信息

Treno A J, Gruenewald P J, Johnson F W

机构信息

Prevention Research Center, Berkeley, CA 94704, USA.

出版信息

Addiction. 1998 Jan;93(1):113-29. doi: 10.1046/j.1360-0443.1998.93111311.x.

Abstract

AIMS

Injury location, injury cause and patient drinking patterns were used to predict blood alcohol content (BAC) and self-reported drinking before injury using emergency room (ER) data.

DESIGN

Models estimating both BAC and self-reported drinking among emergency room injury patients were used; the ER sample was also compared to an injured sample from the general population.

SETTING

Data were from three of six communities participating in the project "Preventing Alcohol Trauma: a community trial".

PARTICIPANTS

ER data were collected from nine hospitals on Friday and Saturday nights between 6 p.m. and 2 a.m. on alternate weekends from June 1992 to December 1995. Telephone survey data were collected between April 1992 and March 1996.

MEASUREMENTS

Drinking measures included drinking frequency, drinks per occasion, and variance. Other measures involved injury time, location, and type; drinking before and after injury; and age, race, gender, education, marital status and household income. Model estimation corrected both for selection bias and censoring of the dependent measure.

FINDINGS

The results indicate: (1) ER populations tended to be female, less well educated, non-white, poor and younger; (2) there were significant selection bias effects in the ER sample; (3) assaults were more likely to involve drinking than other injury types; (4) drinking patterns were significant non-linear predictors of alcohol involvement; and (5) self-reported drinking before injury was both a sensitive and specific indicator of measured BAC.

CONCLUSIONS

Assaults uniquely involve the use of alcohol and selection bias may threaten ER study validity.

摘要

目的

利用急诊室(ER)数据,通过损伤部位、损伤原因和患者饮酒模式来预测损伤前的血液酒精含量(BAC)和自我报告的饮酒情况。

设计

使用了估计急诊室受伤患者BAC和自我报告饮酒情况的模型;还将急诊室样本与来自普通人群的受伤样本进行了比较。

地点

数据来自参与“预防酒精性创伤:一项社区试验”项目的六个社区中的三个。

参与者

1992年6月至1995年12月期间,在交替的周末晚上6点至凌晨2点,从九家医院收集急诊室数据。1992年4月至1996年3月期间收集电话调查数据。

测量

饮酒测量包括饮酒频率、每次饮酒量和差异。其他测量涉及受伤时间、部位和类型;受伤前后的饮酒情况;以及年龄、种族、性别、教育程度、婚姻状况和家庭收入。模型估计对选择偏倚和因变量测量的删失进行了校正。

结果

结果表明:(1)急诊室人群倾向于女性、受教育程度较低、非白人、贫困且年轻;(2)急诊室样本中存在显著的选择偏倚效应;(3)与其他损伤类型相比,袭击更有可能涉及饮酒;(4)饮酒模式是酒精参与的显著非线性预测因素;(5)损伤前自我报告的饮酒情况是测量的BAC的敏感且特异指标。

结论

袭击独特地涉及酒精使用,选择偏倚可能威胁急诊室研究的有效性。

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