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在急诊伤害病例中,自我报告的饮酒量与 BAC 水平之间的关系:是一条直线吗?

The relationship between self-reported drinking and BAC level in emergency room injury cases: is it a straight line?

机构信息

Alcohol Research Group, Emeryville, California 94608, USA.

出版信息

Alcohol Clin Exp Res. 2010 Jun;34(6):1118-25. doi: 10.1111/j.1530-0277.2010.01188.x. Epub 2010 Apr 5.

Abstract

BACKGROUND

While the validity of self-reported consumption based on blood alcohol concentration (BAC) has been found to be high in emergency room (ER) samples, little research exists on the estimated number of drinks consumed given a BAC level. Such data would be useful in establishing a dose-response relationship between drinking and risk (e.g., of injury) in those studies for which the number of drinks consumed is not available but BAC is.

METHODS

Several methods were used to estimate the number of drinks consumed in the 6 hours prior to injury based on BAC obtained at the time of ER admission of n = 1,953 patients who self-reported any drinking 6 hours prior to their injury and who arrived to the ER within 6 hours of the event, from the merged Emergency Room Collaborative Alcohol Analysis Project (ERCAAP) and the World Health Organization Collaborative Study on Alcohol and Injury across 16 countries.

RESULTS

The relationship between self-reported consumption and averaged BAC within each consumption level appeared to be fairly linear up to about 7 drinks and a BAC of approximately 100 mg/dl. Above about 7 reported drinks, BAC appeared to have no relationship with drinking, possibly representing longer consumption periods than only the 6 hours before injury for those reporting higher quantities consumed. Both the volume estimate from the bivariate BAC to self-report relationship as well as from a Widmark calculation using BAC and time from last drink to arrival to the ER indicated a somewhat weak relationship to actual number of self-reported drinks.

CONCLUSIONS

Future studies may benefit from investigating the factors suspected to be driving the weak relationships between these measures, including the actual time over which the reported alcohol was consumed and pattern of drinking over the consumption period.

摘要

背景

虽然基于血液酒精浓度(BAC)的自我报告饮酒量的有效性已在急诊室(ER)样本中得到证实,但对于给定 BAC 水平下估计的饮酒量,研究甚少。在那些无法获得饮酒量但可以获得 BAC 的研究中,此类数据对于建立饮酒与风险(例如受伤风险)之间的剂量反应关系非常有用。

方法

我们使用了几种方法,根据 n = 1953 名在 ER 就诊时自我报告在受伤前 6 小时内有任何饮酒且在事件发生后 6 小时内到达 ER 的患者的 BAC 来估计他们在受伤前 6 小时内饮用的饮料数量,这些患者来自合并的急诊室协作酒精分析项目(ERCAAP)和世界卫生组织在 16 个国家开展的酒精与伤害合作研究。

结果

在每个饮酒水平内,自我报告的饮酒量与平均 BAC 之间的关系似乎相当线性,直到大约 7 杯和大约 100mg/dl 的 BAC。在大约 7 杯以上的报告饮酒量之后,BAC 似乎与饮酒没有关系,可能代表着对于那些报告饮用更多数量的人来说,饮酒时间比受伤前的 6 小时更长。从双变量 BAC 到自我报告关系以及从使用 BAC 和从最后一次饮酒到到达 ER 的时间进行的 Widmark 计算得出的体积估计都表明与实际报告的饮酒量之间存在较弱的关系。

结论

未来的研究可能受益于调查被怀疑导致这些测量之间弱关系的因素,包括报告的酒精实际消耗时间和消耗期间的饮酒模式。

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