Kolb F E, Brenner K V, Lachmann G, Körber R, Kouider S
Arch Exp Veterinarmed. 1976 Jan 1;30(1):93-107.
Different quantities of sorbite-electrolyte solution were intravenously administered to eight heads of cattle and four heads of sheep (application values being 50 g sorbite, 0.3049 g MgCl2-6H2O, 0.3728 g KCl, 0.5477 g CaCl2-6H2O, 5.265 g NaCl, 6.804 g sodium acetate-3H2O with 1,000 ml distilled water). Different rises of sorbite, fructose, and glucose were recorded from the blood plasma. Certain manifestations of incompatibility and intolerance phenomena were observed, among them increase of cardiorespiratory activity and muscular tremor. Those findings were obtained primarily from animals which exhibited also strong rise in glucose concentration. One of the sheep died. Larger quantities of solution (2,000 ml or 4,000 ml) were intraperitoneally applied to ten heads of cattle and tolerated by them with no reaction. Sorbite in blood plasma usually reached its maximum two or three hours from application, however, without any rise of fructose or glucose. Slow drip infusion or intraperitoneal infusion are the techniques recommended for application of the above sorbite-electrolyte solution to ruminants.
向八头牛和四只羊静脉注射不同量的山梨醇电解质溶液(应用值为50克山梨醇、0.3049克六水合氯化镁、0.3728克氯化钾、0.5477克六水合氯化钙、5.265克氯化钠、6.804克三水合醋酸钠加1000毫升蒸馏水)。记录到血浆中山梨醇、果糖和葡萄糖有不同程度的升高。观察到了一些不相容和不耐受现象的表现,其中包括心肺活动增加和肌肉震颤。这些发现主要来自血糖浓度也大幅升高的动物。有一只羊死亡。向十头牛腹腔注射了较大剂量的溶液(2000毫升或4000毫升),它们耐受良好,没有出现任何反应。血浆中的山梨醇通常在注射后两到三个小时达到峰值,然而,果糖或葡萄糖并没有升高。缓慢滴注或腹腔内注射是将上述山梨醇电解质溶液应用于反刍动物的推荐技术。