[Mesothelioma in syrian hamster. V. Macroscopic and histologic investigation of transplanted mesothelioma in solid and ascitic form (author's transl)].

Transplantable mesothelioma lines are described, which have been inoculated successively either s.c. or i.p. in solid and ascitic form. Increases of the degree of malignancy could be demonstrated for macroscopically biological parameters. The latent periods became shorter with increasing in vivo passages. In the histological picture, progressive dedifferentiation of the tumour cells with rising tendency towards infiltrative growth was observed.