Hu F R, Lin J C, Chiang I P, Yeh K H
Department of Ophthalmology, National Taiwan University Hospital, Taipei.
Am J Ophthalmol. 1998 May;125(5):717-9. doi: 10.1016/s0002-9394(98)00012-9.
To report a rare case of T-cell malignant lymphoma involving the conjunctiva.
A 63-year-old woman had rapid onset of bilateral perilimbal congestion and chemosis. Perilimbal thickening with corneal infiltration developed 20 days later. Computed tomography incidentally disclosed a right maxillary sinus mass. Biopsy specimens from the maxillary sinus mass and the left limbus were subjected to histopathologic examination and immunohistochemical study.
T-cell malignant lymphoma of diffuse large cell type, stage IV, was diagnosed. The patient was treated with combination chemotherapy plus 13-cis-retinoic acid and remained in remission 1 1/2 years after diagnosis.
Conjunctival involvement with T-cell lymphoma may present as episcleritis and chemosis.
报告1例累及结膜的罕见T细胞恶性淋巴瘤病例。
1名63岁女性双眼睑缘迅速出现充血和结膜水肿。20天后出现睑缘增厚伴角膜浸润。计算机断层扫描偶然发现右侧上颌窦肿物。对上颌窦肿物和左侧角膜缘的活检标本进行组织病理学检查和免疫组化研究。
诊断为弥漫大细胞型T细胞恶性淋巴瘤,IV期。患者接受联合化疗加13 - 顺式维甲酸治疗,诊断后1年半仍处于缓解期。
T细胞淋巴瘤累及结膜可表现为巩膜炎和结膜水肿。