David J, Grewal R S
J Med Primatol. 1977;6(6):337-43. doi: 10.1159/000459769.
Ninety-five out of 100 male Macaca mulatta of varying ages from a restricted habitat in N. India showed no abnormal seizure susceptibility or EEG response to photic stimulation and no electro-clinical features of epilepsy after pentylenetetrazol, 40 mg/kg sc.c. Autopsy studies on the remaining five monkeys with increased seizure proneness revealed depressed skull fractures with cortical trauma in four and a neoplasm in one. Presumably, these factors were responsible for the lowered seizure susceptibility to photic stimulation and pentylenetetrazol activation.
从印度北部一个有限栖息地选取了100只不同年龄的雄性恒河猴，其中95只对光刺激无异常癫痫易感性或脑电图反应，在腹腔注射40mg/kg戊四氮后也无癫痫的电临床特征。对其余五只癫痫易感性增加的猴子进行尸检研究发现，四只猴子有颅骨凹陷性骨折伴皮质损伤，一只猴子有肿瘤。据推测，这些因素导致了对光刺激和戊四氮激活的癫痫易感性降低。
