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恒河猴的无性细胞瘤:形态学和生物学特征

Dysgerminoma in a rhesus monkey: morphologic and biological features.

作者信息

Holmberg C A, Sesline D, Osburn B

出版信息

J Med Primatol. 1978;7(1):53-8. doi: 10.1159/000459785.

Abstract

A female Macaca mulatta was observed for 31 months after the initial surgical removal of an ovarian tumor. Solitary metastatic lesions were surgically removed 26 and 28 months after excision of the primary tumor. The animal was killed after 31 months because of additional metastatic lesions. Histological evaluation by light microscopy was not conclusive in determining the origin of neoplasm. Transmission electron microscopy, lymphocyte marker studies, and hormone assays were utilized to confirm the diagnosis of dysgerminoma.

摘要

对一只雌性恒河猴在初次手术切除卵巢肿瘤后进行了31个月的观察。在原发性肿瘤切除后26个月和28个月,通过手术切除了孤立的转移病灶。31个月后,由于出现更多转移病灶,该动物被处死。光镜下的组织学评估在确定肿瘤起源方面并不明确。利用透射电子显微镜、淋巴细胞标志物研究和激素测定来确诊无性细胞瘤。

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