ABO血型不相容与葡萄糖-6-磷酸脱氢酶缺乏症的联合作用：对溶血和新生儿高胆红素血症的影响。
Combination of ABO blood group incompatibility and glucose-6-phosphate dehydrogenase deficiency: effect on hemolysis and neonatal hyperbilirubinemia.
作者信息
Kaplan M, Vreman H J, Hammerman C, Leiter C, Rudensky B, MacDonald M G, Stevenson D K
机构信息
Department of Neonatology, Shaare Zedek Medical Center, Hebrew University, Hadassah Medical School, Jerusalem, Israel.
出版信息
Acta Paediatr. 1998 Apr;87(4):455-7. doi: 10.1080/08035259850157093.
The incidence (%) of hyperbilirubinemia (serum bilirubin > or = 257 micromol/l) was similar in neonates with a combination of ABO incompatibility and glucose-6-phosphate dehydrogenase (G-6-PD) deficiency (45%), with ABO incompatibility (54%) or G-6-PD deficiency (37%), alone (ns). Carboxyhemoglobin values, corrected for inspired CO, were similarly elevated in all three groups (0.87 +/- 0.32%, 0.82 +/- 0.29%, 0.76 +/- 0.18%, respectively, ns), but correlated with bilirubin only in those with ABO incompatibility alone. ABO-incompatible/G-6-PD-deficient neonates, compared with those with either condition alone, are not at increased risk for hemolysis or hyperbilirubinemia.
患有ABO血型不合与葡萄糖-6-磷酸脱氢酶（G-6-PD）缺乏症合并症的新生儿中，高胆红素血症（血清胆红素≥257微摩尔/升）的发生率（%）为45%，与单独患有ABO血型不合（54%）或G-6-PD缺乏症（37%）的新生儿相似（无显著性差异）。校正吸入一氧化碳后的碳氧血红蛋白值在所有三组中同样升高（分别为0.87±0.32%、0.82±0.29%、0.76±0.18%，无显著性差异），但仅在单独患有ABO血型不合的新生儿中与胆红素相关。与单独患有这两种病症之一的新生儿相比，患有ABO血型不合/G-6-PD缺乏症的新生儿发生溶血或高胆红素血症的风险并未增加。
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