Veiga González M, Fresno Forcelledo M F, Pérez del Río M J, Madrigal Rubiales B, Vara Castrodeza A, Herrero Zapatero A
Servicio de Anatomía Patológica, Hospital Central de Asturias (Hospital Covadonga), Universidad de Oviedo.
An Med Interna. 1998 May;15(5):262-4.
A case of extramedullary plasmacytoma of the maxillary sinus, locally aggressive, in a 65 years old man is presented. Clinical diagnosis of adenocarcinoma was suspected but the pathological study showed an anaplastic morphology, with little plasmacytic differentiation and lack of stain with cytokeratins and epithelial membrane antigen (EMA), immunohistochemical marker of plasmatic cells, among others. Definitive diagnosis was based on light chain restriction and lack of multiple myeloma.
本文报告一例65岁男性上颌窦髓外浆细胞瘤，具有局部侵袭性。临床怀疑为腺癌，但病理研究显示为间变性形态，几乎没有浆细胞分化，细胞角蛋白和上皮膜抗原（EMA）染色阴性，EMA是浆细胞的免疫组化标志物之一。最终诊断基于轻链限制和无多发性骨髓瘤。
