促肾上腺皮质激素分泌型嗜铬细胞瘤

Adrenocorticotropic hormone-secreting pheochromocytoma.

作者信息

Sato M, Watanabe T, Ashikaga T, Taneda T, Yamawake N, Nishizaki M, Arimura A, Azegami N, Arita M, Fukuoka H, Kitamura H

机构信息

First Department of Internal Medicine, Yokohama Minami Kyosai Hospital.

出版信息

Intern Med. 1998 Apr;37(4):403-6. doi: 10.2169/internalmedicine.37.403.

DOI:10.2169/internalmedicine.37.403

PMID:9630203

Abstract

A 41-year-old female had pheochromocytoma which secreted adrenocorticotropic hormone (ACTH). She was admitted to our hospital because of weight loss and excessive sweating. Not only urinary metanephrine but also plasma ACTH was extremely high. An abdominal echogram showed a cystic tumor in the left adrenal gland. An abdominal magnetic resonance imaging scan showed a hyperintense T2-weighted abnormality inside the tumor. Left adrenalectomy was done. The tumor consisted of benign pheochromocytoma cells diffusely stained with anti-ACTH antibody. The present case did not show any typical Cushingoid symptoms which are common in ACTH-secreting pheochromocytomas.

摘要

一名41岁女性患有分泌促肾上腺皮质激素（ACTH）的嗜铬细胞瘤。她因体重减轻和多汗入院。不仅尿间甲肾上腺素，而且血浆ACTH都极高。腹部超声检查显示左肾上腺有一个囊性肿瘤。腹部磁共振成像扫描显示肿瘤内部在T2加权像上有高信号异常。进行了左肾上腺切除术。肿瘤由良性嗜铬细胞瘤细胞组成，用抗ACTH抗体弥漫性染色。本例未表现出分泌ACTH的嗜铬细胞瘤常见的任何典型库欣样症状。