Langin T, Pépin J L, Pendlebury S, Baranton-Cantin H, Ferretti G, Reyt E, Lévy P
Department of Respiratory Medicine, the Sleep Laboratory, CHU de Grenoble, France.
Chest. 1998 Jun;113(6):1595-603. doi: 10.1378/chest.113.6.1595.
We used upper airway (UA) imaging in 20 patients to determine (1) whether an effective enlargement of the UA is obtained after uvulopalatopharyngoplasty (UPPP), and (2) whether UA modifications explain the results of such surgery.
Cephalometric measurements were made to assess the posterior airway space, the length and width of the soft palate, and the distance between the hyoid bone and the mandibular plane. Pharyngeal CT measured the airway cross-sectional area (CSA) at each 10-mm slice from 10 mm above (-10) to 40 mm below (+40) the hard palate. Polysomnography was performed before and after surgery (10+/-10 [SD] months). Good responders were defined by an apnea-hypopnea index (AHI) of <10 postsurgery or, in patients in whom AHI was initially <10, a reduction of AHI >50% of the initial AHI.
Twenty patients (age=45+/-11 years) were studied. For the whole group, the mean body mass index (26+/-4 kg/m2) and AHI (14+/-13 vs 18+/-16/h) were unchanged after UPPP. The results of the surgery were mediocre with 7 good responders (35%) and 13 nonresponders (65%) defined by polysomnographic criteria. The only changes on UA imaging for the group as a whole after UPPP were decrease in length (40+/-6 vs 29+/-5 mm, p< or =0.0006) and increase in width of the soft palate (11.5+/-2.7 vs 13.6+/-3.5 mm, p< or =0.006). The increase or decrease in minimal CSA at the oropharyngeal (OP) level after UPPP was significantly correlated with the change in AHI (r=-0.54, p<0.02). Moreover, the changes in CSA obtained at the OP level were significant only in the patients who responded favorably to UPPP (7 vs 13 nonresponders).
Postoperative OP enlargement is associated with a good outcome of UPPP. Persistent narrowing in nonresponders could be due to the increase in soft palate width after surgery.
我们对20例患者进行上气道(UA)成像,以确定:(1)悬雍垂腭咽成形术(UPPP)后是否能有效扩大UA;(2)UA的改变是否能解释该手术的效果。
进行头影测量以评估后气道间隙、软腭的长度和宽度以及舌骨与下颌平面之间的距离。咽部CT测量从硬腭上方10毫米(-10)至下方40毫米(+40)每10毫米切片处的气道横截面积(CSA)。在手术前后(10±10[标准差]个月)进行多导睡眠监测。手术效果良好的定义为术后呼吸暂停低通气指数(AHI)<10,或者对于初始AHI<10的患者,AHI降低幅度>初始AHI的50%。
研究了20例患者(年龄=45±11岁)。对于整个组,UPPP后平均体重指数(26±4kg/m²)和AHI(14±13对18±16次/小时)未改变。根据多导睡眠监测标准,手术效果一般,7例手术效果良好者(35%)和13例无反应者(65%)。UPPP后整个组UA成像的唯一变化是长度缩短(40±6对29±5毫米,p≤0.0006)和软腭宽度增加(11.5±2.7对13.6±3.5毫米,p≤0.006)。UPPP后口咽(OP)水平最小CSA的增加或减少与AHI的变化显著相关(r=-0.54,p<0.02)。此外,仅在对UPPP反应良好的患者中,OP水平获得的CSA变化才显著(7例对13例无反应者)。
术后OP扩大与UPPP的良好效果相关。无反应者持续狭窄可能是由于手术后软腭宽度增加。