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腹腔镜肾盂成形术。适应症、技术及长期疗效。

Laparoscopic pyeloplasty. Indications, technique, and long-term outcome.

作者信息

Chen R N, Moore R G, Kavoussi L R

机构信息

James Buchanan Brady Urological Institute, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, USA.

出版信息

Urol Clin North Am. 1998 May;25(2):323-30. doi: 10.1016/s0094-0143(05)70021-5.

DOI:10.1016/s0094-0143(05)70021-5
PMID:9633588
Abstract

Laparoscopic pyeloplasty is one of several minimally invasive treatment options for UPJ obstruction. In fact, several endoscopically and fluoroscopically controlled methods of incising the obstructed UPJ are now available that are significantly less invasive and less morbid in comparison with open pyeloplasty. However, the long-term success rates of these incisional techniques are less than the rates reported for open pyeloplasty. Several causes of obstruction may be present in the primarily obstructed UPJ, including kinking or compression related to crossing vessels or intrinsic narrowing at the UPJ. One potential reason for the inferior success rates of incisional methods in comparison with open pyeloplasty is that the former techniques address the intrinsically narrowed UPJ but may not address extrinsic problems such as kinking of the ureter associated with fibrotic bands or compression from crossing vessels. Laparoscopic pyeloplasty addresses all potential causes of obstruction. Any fibrotic bands kinking the ureter are divided, and the ureter is spatulated through the level of the UPJ prior to completion of the anastomosis. If a crossing vessel is encountered, a dismembered pyeloplasty is performed, the ureter and renal pelvis are transposed to the opposite side of the vessels, and the anastomosis is completed. An additional disadvantage of incisional techniques is the significant risk of hemorrhage following incision of the UPJ, with as many as 3% to 11% of patients requiring blood transfusion. Hemorrhage may occur owing to an errant anterior incision, the presence of a crossing vessel, incision into the renal parenchyma adjacent to the UPJ, or as the result of bleeding from the percutaneous access site. In contrast, mean estimated blood loss in the authors' series of 57 laparoscopic pyeloplasties was 139 mL, and none of the patients required blood transfusion. Although it is more morbid in comparison with retrograde or fluoroscopically controlled endopyelotomy, laparoscopic pyeloplasty seems at least comparable to antegrade percutaneous endopyelotomy in terms of the length of hospitalization and patient convalescence. Laparoscopic pyeloplasty, however, offers a higher success rate than with incisional techniques, not only from a radiographic standpoint but from a subjective standpoint as determined by the results of the analogue pain and activity questionnaire. The major disadvantage of laparoscopic pyeloplasty is the need for proficiency in laparoscopic techniques and for a longer operative time. As a result, the literature on laparoscopic pyeloplasty consists primarily of small series. Janetschek and co-workers reported on a series of 17 patients who underwent laparoscopic pyeloplasty, including 14 via a transperitoneal approach and 3 via a retroperitoneal approach. Procedures performed included ureterolysis alone, dismembered pyeloplasty, and nondismembered (Fenger) pyeloplasty. "Fenger-plasty" is similar to Y-V pyeloplasty and is performed by incising the UPJ longitudinally and closing the incision transversely in a Heineke-Mikulicz fashion. Janetschek and colleagues reported a 100% success in the eight patients who underwent dismembered pyeloplasty but believed that this technique was too cumbersome and should be reserved for patients with long stenoses, dorsally crossing vessels, or large renal pelvis. Because two of the four patients undergoing ureterolysis alone failed treatment, Janetschek and colleagues have abandoned this technique. They now prefer the Fenger-plasty technique, even in the setting of ventrally crossing vessels, because the technique can be performed quickly with one to three sutures, and the anastomosis can be sealed with fibrin glue and a flap of Gerota's fascia. Their experience with this technique, however, remains relatively limited. Technologic advances such as the Endostitch device have facilitated reconstructive laparoscopic procedures such as pyeloplasty. (ABSTRACT TRUNCATED)

摘要

腹腔镜肾盂成形术是治疗肾盂输尿管连接部(UPJ)梗阻的几种微创治疗选择之一。事实上,目前有几种在内镜和荧光镜控制下切开梗阻性UPJ的方法,与开放肾盂成形术相比,这些方法的侵入性明显更小,并发症也更少。然而,这些切开技术的长期成功率低于开放肾盂成形术报道的成功率。原发性梗阻性UPJ可能存在多种梗阻原因,包括与交叉血管相关的扭结或压迫,或UPJ处的内在狭窄。与开放肾盂成形术相比,切开方法成功率较低的一个潜在原因是,前者技术解决了内在狭窄的UPJ,但可能无法解决外在问题,如与纤维化带相关的输尿管扭结或交叉血管的压迫。腹腔镜肾盂成形术解决了所有潜在的梗阻原因。任何使输尿管扭结的纤维化带都被切断,在完成吻合之前,输尿管在UPJ水平处做成鱼嘴状。如果遇到交叉血管,则进行离断性肾盂成形术,将输尿管和肾盂移位到血管的另一侧,然后完成吻合。切开技术的另一个缺点是切开UPJ后有大出血的显著风险,多达3%至11%的患者需要输血。出血可能由于前侧切口失误、存在交叉血管、切入UPJ附近的肾实质,或经皮穿刺部位出血所致。相比之下,在作者的57例腹腔镜肾盂成形术系列中,平均估计失血量为139毫升,没有患者需要输血。虽然与逆行或荧光镜控制的内镜肾盂切开术相比,腹腔镜肾盂成形术的并发症更多,但就住院时间和患者康复情况而言,腹腔镜肾盂成形术似乎至少与顺行性经皮肾盂切开术相当。然而,腹腔镜肾盂成形术不仅从影像学角度,而且从模拟疼痛和活动问卷结果所确定的主观角度来看,都比切开技术有更高的成功率。腹腔镜肾盂成形术的主要缺点是需要熟练掌握腹腔镜技术,且手术时间较长。因此,关于腹腔镜肾盂成形术的文献主要是小系列报道。扬切克及其同事报道了一组17例接受腹腔镜肾盂成形术的患者,其中14例经腹腔途径,3例经腹膜后途径。所进行的手术包括单纯输尿管松解术、离断性肾盂成形术和非离断性(芬格)肾盂成形术。“芬格成形术”类似于Y-V肾盂成形术,通过纵向切开UPJ并以海涅克-米库利奇方式横向缝合切口来进行。扬切克及其同事报告,8例接受离断性肾盂成形术的患者成功率为100%,但他们认为该技术过于繁琐,应仅用于长段狭窄、背侧交叉血管或肾盂较大的患者。由于4例单纯接受输尿管松解术的患者中有2例治疗失败,扬切克及其同事已放弃该技术。他们现在更喜欢芬格成形术,即使在腹侧交叉血管情况下也是如此,因为该技术用1至3针缝线就能快速完成,吻合口可用纤维蛋白胶和一块肾周筋膜瓣封闭。然而,他们在该技术方面的经验仍然相对有限。诸如Endostitch装置等技术进步促进了诸如肾盂成形术等重建性腹腔镜手术。

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