Efron D, Jarman F C, Barker M J
Centre for Community Child Health & Ambulatory Paediatrics, Royal Children's Hospital, Melbourne, Victoria, Australia.
J Paediatr Child Health. 1998 Jun;34(3):288-92. doi: 10.1046/j.1440-1754.1998.00224.x.
To evaluate child and parent perceptions of treatment with stimulant medication in a sample of children with attention deficit hyperactivity disorder (ADHD).
Child and parent perceptions questionnaires were completed for 102 subjects participating in a double-blind, crossover trial of methylphenidate (MPH) and dexamphetamine (DEX).
Most children viewed medication effects favourably, although 12.7% and 18.8% of children reported feeling worse than usual when taking MPH and DEX, respectively. There was disagreement between the child's and parents' perceptions of response in over one quarter of cases. Most disagreements involved parents viewing the child's response favourably, but the child rating reporting an unfavourable outcome. Side-effects were the main determinant of children's perceptions of adverse response.
A substantial proportion of children with ADHD experience treatment with stimulant medication adversely. Side-effects are the principal determinant of negative child perceptions. Parental report is usually in agreement with child report; however, parental report alone is not infallible in providing reliable information regarding effects as experienced by the child.
在一组注意力缺陷多动障碍(ADHD)儿童样本中,评估儿童及其父母对使用刺激性药物治疗的看法。
为102名参与哌甲酯(MPH)和右旋苯丙胺(DEX)双盲交叉试验的受试者完成了儿童及父母看法调查问卷。
大多数儿童对药物效果持积极看法,尽管分别有12.7%和18.8%的儿童报告在服用MPH和DEX时感觉比平时更糟。在超过四分之一的案例中,儿童和父母对反应的看法存在分歧。大多数分歧涉及父母对儿童反应持积极看法,但儿童评级报告结果不佳。副作用是儿童对不良反应看法的主要决定因素。
相当一部分ADHD儿童对刺激性药物治疗有不良反应。副作用是儿童负面看法的主要决定因素。父母的报告通常与儿童的报告一致;然而,仅父母的报告在提供有关儿童所经历效果的可靠信息方面并非绝对可靠。