膜融合：全都由SNARE蛋白完成？

Membrane fusion: all done with SNAREpins?

作者信息

Edwardson J M

机构信息

Department of Pharmacology, University of Cambridge, UK.

出版信息

Curr Biol. 1998 May 21;8(11):R390-3. doi: 10.1016/s0960-9822(98)70245-3.

DOI:10.1016/s0960-9822(98)70245-3

PMID:9635186

Abstract

SNARE proteins are sufficient to fuse artificial membranes together. In the cell, vesicle transport may rely on fusion mediated by interaction between vesicle (v) and target (t) SNAREs, whereas the homotypic fusion of organelle biogenesis may be mediated by t-SNARE-t-SNARE interaction.

摘要

SNARE蛋白足以使人工膜融合在一起。在细胞中，囊泡运输可能依赖于囊泡（v）和靶标（t）SNARE之间相互作用介导的融合，而细胞器生物发生的同型融合可能由t-SNARE-t-SNARE相互作用介导。