Gallego P, Oliver J M, Benito F, Mesa J M, Sanz E, Moreno I, Cordovilla G
Department of Cardiology, La Paz General Hospital, Autonoma University, Paseo de la Castellana 261, E-28046 Madrid, Spain.
Pediatr Cardiol. 1998 Jul-Aug;19(4):358-60. doi: 10.1007/s002469900323.
A case of unusual longevity to the age of 58 years is reported for a female patient with complete transposition of the great arteries. The association with a wide atrial septal defect with intact interventricular septum may have contributed to the long survival without surgery. Factors determining intercirculatory mixing and systemic oxygen saturation may be the high pulmonary flow, the location of the anatomic communication, sufficient hemoglobin concentration to allow an adequate level of systemic resistance and recirculated systemic flow, and the belated development of pulmonary vascular disease.
报道了一例患有大动脉完全转位的女性患者活到58岁的罕见长寿病例。合并完整室间隔的大型房间隔缺损可能是其未经手术而长期存活的原因。决定体循环-肺循环混合及体循环血氧饱和度的因素可能包括高肺血流量、解剖分流部位、足够的血红蛋白浓度以维持适当水平的体循环阻力和体循环血流再循环,以及肺血管疾病的延迟发生。