[人类免疫缺陷病毒感染中的恶性梅毒]
[Malignant syphilis in human immunodeficiency virus infection].
作者信息
Misery L, Besnard V, Badel R, Marneffe-Delalande E, Faure M, Thivolet J
机构信息
Clinique Dermatologique, Hôpital Edouard Herriot, Lyon, France.
出版信息
Ann Dermatol Venereol. 1996;123(11):732-4.
INTRODUCTION
The associated infection with Treponema pallidum and human immunodeficiency virus (HIV) was responsible for the return of malignant syphilis.
CASE REPORT
We report a case of malignant syphilis which revealed a HIV seropositivity. The lesions were typical. Serological features were in accordance with the diagnosis. A treatment with penicillin was prescribed and there was no relapse after five years.
DISCUSSION
The diagnosis of malignant syphilis in a HIV positive patient may be difficult. The course of the disease may be serious and a prolonged treatment with high doses of penicillin is often necessary. The occurrence of the malignant syphilis in HIV positive patients is not fortuitous and seems to be related to an abnormal immunity.
引言
梅毒螺旋体与人类免疫缺陷病毒（HIV）的合并感染导致恶性梅毒复发。
病例报告
我们报告一例恶性梅毒病例，该病例HIV血清学检测呈阳性。病变典型。血清学特征符合诊断。给予青霉素治疗，五年后无复发。
讨论
HIV阳性患者中恶性梅毒的诊断可能困难。疾病过程可能严重，通常需要大剂量青霉素进行长期治疗。HIV阳性患者中出现恶性梅毒并非偶然，似乎与免疫异常有关。
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