Luo J F, Liu M W, Wong P M, Mathur A, Iyer S S, Baxley W A, Dean L S, Roubin G S
Division of Cardiovascular Diseases, The University of Alabama at Birmingham, 35294, USA.
Cathet Cardiovasc Diagn. 1998 Jun;44(2):144-6. doi: 10.1002/(sici)1097-0304(199806)44:2<144::aid-ccd4>3.0.co;2-6.
The long-term patency of saphenous vein graft (SVG) lesions after intervention has been shown to be improved with new interventional techniques such as stents. Long-term outcome of patients undergoing successful angioplasty of totally occluded old SVGs with new devices is unknown. From July 1994 to June 1996, 19 patients with totally occluded old SVGs had successful angioplasty with new interventional techniques. Mean SVG age was 123 +/- 8 mo. Thrombolysis in myocardial infarction trial (TIMI) flow was 0 in all target lesions. TIMI 2 or 3 flow was restored after angioplasty in all patients. Intracoronary urokinase, transluminal extractional atherectomy, and stenting were used in 14, 12, and 6 patients, respectively. There was one in-hospital death due to ongoing myocardial infarction, no recurrent infarction, and no repeat angioplasty or bypass surgery in the hospital. At follow-up of 21 +/- 1 mo, there was one sudden death and one myocardial infarction. Five patients had repeat coronary bypass surgery, and 4 had repeat angioplasty. Thirteen patients remained asymptomatic, and 4 had angina. The long-term outcome of patients who had successful reopening of occluded old SVGs is encouraging in this small sample.
经证实,采用支架等新的介入技术可改善隐静脉移植物(SVG)病变干预后的长期通畅情况。采用新设备对完全闭塞的陈旧SVG进行成功血管成形术的患者的长期预后尚不清楚。1994年7月至1996年6月,19例完全闭塞的陈旧SVG患者采用新的介入技术成功进行了血管成形术。SVG的平均使用时间为123±8个月。所有靶病变的心肌梗死溶栓试验(TIMI)血流均为0级。血管成形术后所有患者的TIMI 2级或3级血流均得以恢复。分别有14例、12例和6例患者使用了冠状动脉内尿激酶、腔内旋切术和支架置入术。有1例患者因持续性心肌梗死在住院期间死亡,无复发性梗死,住院期间无重复血管成形术或搭桥手术。在21±1个月的随访中,有1例猝死和1例心肌梗死。5例患者接受了再次冠状动脉搭桥手术,4例接受了再次血管成形术。13例患者无症状,4例有心绞痛。在这个小样本中,成功重新开通闭塞的陈旧SVG的患者的长期预后令人鼓舞。