Smith M C
Department of Neurological Sciences, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612-3824, USA.
Epilepsia. 1998;39 Suppl 4:S81-9. doi: 10.1111/j.1528-1157.1998.tb05128.x.
Multiple subpial transection (MST) was developed to permit the treatment of partial epilepsies that reside in or encroach on eloquent cortex (language and sensorimotor cortex). It was conceived after the discoveries of the columnar organization of neocortex and that expression and spread of seizures utilize the transverse fiber network. Although the technique is simple in principle, it takes a skilled and practiced hand to avoid damage to the neocortical columns and vascular supply. The efficacy in controlling seizures with MST in extratemporal epilepsy is similar to that of resective surgery. Activities of daily living are not adversely impacted by MST. MST is a viable alternative to resection in extratemporal epilepsy.
多软膜下横切术（MST）是为治疗位于或侵犯功能区皮质（语言和感觉运动皮质）的部分性癫痫而研发的。它是在发现新皮质的柱状组织以及癫痫发作的表达和传播利用横向纤维网络之后构想出来的。尽管该技术原理简单，但需要熟练且经验丰富的操作才能避免损伤新皮质柱和血管供应。MST在颞叶外癫痫中控制癫痫发作的疗效与切除性手术相似。日常生活活动不会受到MST的不利影响。MST是颞叶外癫痫切除手术的一种可行替代方法。
