Fukino S, Hayashi E, Fukata T, Okada M, Okada K, Makihara K, Morio S
Department of Surgery, Tottori Prefectural Kousei Hospital, Kurayoshi, Japan.
Kyobu Geka. 1998 Jun;51(6):513-6.
The patient was a 75-year-old man complaining of cough in July 1996. Chest X-ray demonstrated a tumor in the left S6. Percutaneous lung biopsy specimen revealed lung cancer. On September 4, 1996, left lobectomy (R 2 a) was performed. The tumor was 3.8 x 3.2 x 2.1 cm in size and showed a white yellow solid mass (pT2N0M0, pStage I, p1d0e0pm0). The pathological examination was confirmed no differentiation in adenocarcinoma and squamous cell carcinoma. More than 90% of the tumor cells were characterized as having large clear cytoplasm. On immunohistochemical study, the tumor cells expressed positive with EMA, CEA, cytokeratin and negative with vimentin. The postoperative findings showed no presence of renal cell carcinoma. As the result, a diagnosis of primary clear cell carcinoma of the lung was made. The postoperative course is uneventful.
该患者为一名75岁男性，于1996年7月出现咳嗽症状。胸部X线检查显示左肺下叶背段（S6）有一肿瘤。经皮肺活检标本显示为肺癌。1996年9月4日，进行了左肺叶切除术（R 2 a）。肿瘤大小为3.8×3.2×2.1 cm，呈灰白色实性肿块（pT2N0M0，pⅠ期，p1d0e0pm0）。病理检查证实腺癌和鳞癌均无分化。超过90%的肿瘤细胞具有大的透明细胞质。免疫组织化学研究显示，肿瘤细胞EMA、CEA、细胞角蛋白呈阳性，波形蛋白呈阴性。术后检查未发现肾细胞癌。因此，诊断为原发性肺透明细胞癌。术后病程平稳。
